UNINDENTIFIED BRIGHT OBJECTS IN BRAIN

30% to 60% of patients with Type I Neurofibramatosis (NF1)  demonstrate hyperintense lesion on T2-weighted MRI in the basal ganglia, thalamus, cerebellum, and brain stem. These lesion are called un-identified bright objects ( UBO'S).
An association was demonstrated between these lesions and learning disabilities in children with NF1.
Pathology of these lesion showed increased water content but not dysplasia or hamartoma.